Type 2 Diabetes: Treatment for Your Diabetes

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Oral Medication for Diabetes

A. Insulin Secretagogues

    glyburide (Diabeta & generics) 2.5-20mg per day
    gliclazide (Diamicron & generics) 80-320mg per day
    gliclazide MR (Diamicron MR & generics) 30-120mg per day
    glimepiride (Amaryl) 1-8mg per day

    nateglinide (Starlix) 60-180mg before meals
    repaglinide (GlucoNorm) 0.5-4mg before meals

  • these medications help the pancreas make more insulin
  • may cause low blood glucose and should be taken with food

B. Biguanides

    Glucophage & generics 500-2500mg per day
    Glumetza 500-2000mg per day

  • works mainly by slowing down the glucose that is released by the liver and should be taken with food

C. Thiazolidinediones (TZD’s)

pioglitazone (Actos & generics) 15-45mg per day
rosiglitazone (Avandia) 2-8mg per day

  • these medications make insulin work better
  • may take up to 12 weeks to see results
  • blood work must be done to check liver function (ordered by your doctor)

Avandamet (rosiglitazone/metformin) 2mg/500mg-8mg/2000mg per day
Avandaryl (rosiglitazone/glimepiride) 4mg/1mg-4mg/4mg per day

D. DPP-4 Inhibitors

saxagliptin (Onglyza) 2.5-5mg/day
sitagliptin (Januvia) 100mg/day
vildagliptin (Trajenta) 5mg once daily

  • enhances the body's own ability to control blood sugar levels

Janumet (sitagliptin/metformin) 100mg/1000mg-100mg/2000mg per day
Jentadueto (linagliptin/metformin) 5mg/1000mg-5mg/2000mg per day
Kombiglyze (saxagliptin/metformin) 5mg/1000mg-5mg/2000mg per day

E. Alpha-glucosidase Inhibitor

acarbose (Glucobay) 25-100mg before meals

  • slows rate of carbohydrate absorption to keep blood glucose lower after meals
  • should be taken with the first bite of food at each meal

Handout: oral medications for diabetes

diabetes oral medications

Last updated: Wed, 2013-06-19 15:56