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Celebrating health research excellence with the 2023 Lawson Impact Awards
For the first time since 2019, Lawson Health Research Institute hosted its annual Lawson Impact Awards in-person on November 28 at RBC Place London. Approximately 130 people gathered to celebrate scientists, staff members, learners and partners who have made remarkable contributions to hospital-based research at London Health Sciences Centre (LHSC) and St. Joseph’s Health Care London (St. Joseph’s).
“Important and groundbreaking science is conducted daily at Lawson, improving patient care locally and around the globe,” says Dr. David Hill, Scientific Director at Lawson. “The Lawson Impact Awards provides an opportunity for us to recognize the scientists, staff members, learners and partners who drive medical research forward.”

Eight Lawson Impact Award recipients were celebrated at the event, including:
- Leadership Award for Fellows & Students: Dr. John Tran
- Staff Award of Excellence: Alexandria Roa Agudelo
- Community Partner of the Year Award: Keith and Leanne Lavergne
- Community Partner of the Year Award: Jack and Jean Wettlaufer Family
- Community Partner of the Year Award: Ryan Finch
- Dr. Joseph Gilbert Research Contribution of The Year Award: Dr. David Palma for “Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial”
- Innovation Award: Dr. Manuel Montero-Odasso
- Scientist of The Year Award: Dr. Cheryl Forchuk
Two Children’s Health Research Institute (CHRI) award recipients were also recognized. As a program of Lawson, CHRI awards a Scientist and Trainee of the Year annually, sponsored by the Children’s Health Foundation. CHRI’s 2022 award recipients are: Dr. Emma Duerden (CHRI Scientist of the Year) and Kendrick Lee (CHRI Deb Comuzzi Trainee of the Year).
“This year, we recognized a number of leading research professionals from across LHSC and St. Joseph’s who are helping to advance patient care in London and around the world,” adds Dr. Hill. “We were also honoured to recognize three Community Partners of the Year for their generous support of health research.”
Learn more about each recipient on our Impact Awards page and visit the Lawson YouTube channel to watch videos highlighting each of the award recipients.
Celebrating International Women’s Day
To mark International Women’s Day, two early career researchers at Lawson Health Research Institute are sharing their experiences as women in STEM (science, technology, engineering and math). They shared the support they’ve experienced in their careers, the importance of women’s voices in medical research and how to encourage more women to pursue careers in STEM.
Early access and mentorship are key: Dr. Funmbi Babalola
Dr. Babalola is a Paediatric Endocrinologist at Children’s Hospital at London Health Sciences Centre (LHSC) and an Associate Scientist at Lawson Health Research Institute. She helped pioneer the start of a Paediatric Rare Bone Disease Clinic at Children’s Hospital in 2022 which provides multi-disciplinary care for patients, so they no longer have to travel outside of London for treatment. As a clinician researcher, her areas of interest are paediatric diabetes and calcium and bone metabolism disorders. She is currently involved in several clinical trials and studies.
She credits mentorship and the support of educators early in her career journey with encouraging her interest in science and says that is key for being more welcoming to women in STEM.
“In Grade 12 my biology teacher recommended I go to an advanced placement school. That was when I had my first experience with research,” says Dr. Babalola. “When I got to my undergraduate work, I found a woman mentor who was a powerhouse and had a vision, and I was able to publish two papers during that time and had such a positive experience. I went straight to medical school after that and continued to do research. I think I’ve been really lucky with all the people that I’ve worked with and who have encouraged me as I built my research career.”
Dr. Babalola says she is fortunate to be a researcher in a time when women’s voices are finally being heard and welcomed.
“I think my perspective is probably different than women who were starting work 10 or 20 years ago,” she notes. “I think I’m very lucky that I entered the medical research world where a lot of women are at the table. They’re great role models and they really support and help each other.”
But she says support for research in hospitals is also crucial.
“It takes both good mentors and a culture of research to make it easier to get studies done.”
Dr. Babalola has already started mentoring new researchers, many of them women, who have approached her.
“I’m all about paying it forward. I’ve been super fortunate to have great mentors that are still continuing to mentor me, so I want to pass that knowledge on.”
Women in science are inspirational: Dr. Kait Al
Dr. Kait Al is a Postdoctoral Research Fellow at Western University’s Schulich School of Medicine & Dentistry, working in a Lawson Health Research Institute lab at St. Joseph’s Health Care London. Dr. Al’s research focus is the role of the microbiome in urological conditions like kidney stone disease. She’s currently looking at how a microbiome with beneficial microbes could help protect healthy individuals from forming kidney stones and how optimizing the microbiome could help prevent stone recurrence in stone formers.
She believes women’s voices need to be included in research so that it is more representative of the world we live in and better addresses everyone’s health needs.
“Women bring diverse experiences and perspectives that have been historically excluded from research, along with many other underrepresented groups.”
And mentors among those voices are one of the best ways to encourage more women to get interested in science, she says, so women can see themselves in those positions.
“Seeing someone like yourself as a role model in a successful position that is passionate and curious about science can be so influential to young people,” shares Dr. Al. “As scientists, it’s important to share your work widely.”
She notes that organizations that encourage and support mentorship, as well as a flexible work culture and networking opportunities, are likely to be more welcoming to women in STEM and benefit from having them as part of the team.
“It is crucial to prioritize an inclusive and supportive mentorship environment for trainees and professionals,” says Dr. Al. “I believe work that lets you balance professional and personal commitments, which can otherwise be biased against women, is key.”
The theme for International Women’s Day in 2024 is ‘Inspire Inclusion,’ and that’s exactly what Dr. Al says she sees in other women in science.
“I am constantly inspired by women in science, from my direct colleagues to world leaders I’ve never met. I have witnessed firsthand my colleagues breaking down barriers, succeeding in challenging areas, and lifting each other up, and it really creates a culture of empowerment.”
Check out LHSC's 2017 Report to the Community
London Health Sciences Centre’s 2017 Report to the Community is now online. Take a look at the incredible work of LHSC staff, physicians and volunteers this past year, which has led to milestone achievements, medical ‘firsts’ and strengthened partnerships with local and regional health-care and community agencies. The integrated care model achieved through these partnerships is vital in this time of ongoing system transformation, and LHSC is well positioned for these changing times.
Included in the 2017 Report to the Communtity is a spotlight on Lawson Health Research Institute as the research arm of LHSC.
Children born in Sarnia at higher risk of developing asthma, compared to London and Windsor
LONDON, ON – New findings from Ontario have shown that children born in Sarnia have a higher risk of developing asthma compared to neighbouring cities. A research team from Lawson Health Research Institute and Western University, using provincial data from ICES, found that higher air pollution exposure in the first year of life very likely contributed to this higher risk. Their results are published today in CMAJ Open.
Summary of study results:
- Children born in Sarnia in the 1990s and early 2000s were disproportionally at a higher risk of developing asthma in the first few years of life, compared to neighbouring cities.
- Air pollution exposure in the first year was found to be associated with the development of asthma in children.
- Overall rates of new childhood asthma diagnosis in Southwestern Ontario have been decreasing over time in parallel to decreases in air pollution levels.
“It’s known that cities in Southwestern Ontario have varied levels of air pollution because of differences in industry and traffic. For example, Sarnia is home to the ‘Chemical Valley’ where numerous chemical plants and oil refineries are clustered,” says Dr. Dhenuka Radhakrishnan, an Adjunct ICES Scientist, formerly working out of ICES Western in London, and Pediatric Respirologist at CHEO. “We wanted to see if children born in three cities – London, Windsor and Sarnia – had a different risk of developing asthma due to the differing air pollution levels in the three regions, even though the people living in these cities are otherwise comparable in many ways.”
The researchers followed 114,427 children born in these cities between 1993 and 2009 for 10 years, and found that those in Sarnia were at the highest risk of developing asthma. The researchers found that by the age of 10, nearly 24 per cent of children in Sarnia were diagnosed with asthma, compared to 21 per cent in Windsor and 17 per cent in London. The differences were also present after accounting for many risk factors associated with asthma, such as sex, socioeconomic status and urban versus rural setting. The findings were most apparent in the first two years of life, but persistent beyond the age of six.
“Reassuringly, we found the asthma risk for children has reduced in more recent years as pollution levels have also decreased,” adds Dr. Radhakrishnan.
Asthma is the most common chronic disease in Canadian children and has significant impact on quality of life. Asthma is the leading cause of emergency department visits and hospital admissions in this age group.
“It’s important to find strategies to prevent asthma development and this study suggests that reducing air pollution exposure, including environmental causes, might reduce the number of children who suffer from asthma,” explains Dr. Salimah Shariff, Associate Scientist at Lawson, Adjunct Professor at Western and Scientist at ICES Western.
There is also growing evidence that exposure during pregnancy can influence development of asthma in children. “We need to carefully examine how reducing air pollution exposures within a geographic area translates to reductions in asthma development. Understanding the amount of air pollution that a mother and infant are exposed to, and how this impacts their personal risk, could enable regions to target safer levels for their residents,” adds Dr. Shariff.
Wednesday, May 5 is World Asthma Day (WAD). Recognizing symptoms of asthma early is the best a parent can do to improve the health of their child, so they can be diagnosed quickly and start appropriate treatments. If a parent notices their child has wheezing, persistent cough or difficulty with exercise, they are encouraged to bring this to the attention of a health care provider.
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DOWNLOADABLE MEDIA
Child using an age-appropriate valved spacer device with an asthma inhaler. They should be used together for children to ensure the medication is properly delivered to the lungs.
Child using an age-appropriate valved spacer device with an asthma inhaler. They should be used together for children to ensure the medication is properly delivered to the lungs.
Dr. Dhenuka Radhakrishnan, an Adjunct ICES Scientist, formerly working out of ICES Western in London, and Pediatric Respirologist at CHEO
Dr. Salimah Shariff, Associate Scientist at Lawson, Adjunct Professor at Western and Scientist at ICES Western
Proportion of children with an asthma diagnosis by studied region
Lawson Health Research Institute is one of Canada’s top hospital-based research institutes, tackling the most pressing challenges in health care. As the research institute of London Health Sciences Centre and St. Joseph’s Health Care London, our innovation happens where care is delivered. Lawson research teams are at the leading-edge of science with the goal of improving health and the delivery of care for patients. Working in partnership with Western University, our researchers are encouraged to pursue their curiosity, collaborate often and share their discoveries widely. Research conducted through Lawson makes a difference in the lives of patients, families and communities around the world. To learn more, visit www.lawsonresearch.ca.
Western delivers an academic experience second to none. Since 1878, The Western Experience has combined academic excellence with life-long opportunities for intellectual, social and cultural growth in order to better serve our communities. Our research excellence expands knowledge and drives discovery with real-world application. Western attracts individuals with a broad worldview, seeking to study, influence and lead in the international community.
The Institute for Clinical Evaluative Sciences (ICES) is an independent, non-profit organization that uses population-based health information to produce knowledge on a broad range of health care issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting health care needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad, and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on Twitter: @ICESOntario
Senior Media Relations Consultant
Communications & Public Engagement
T: 519-685-8500 ext. 73502
Celine.zadorsky@lhsc.on.ca
CIHR funding is enabling Lawson research
16 Lawson researchers with primary hospital appointments and affiliated scientists working through Western University are the recipients of project and bridge funding from the Canadian Institutes of Health Research (CIHR).
Lawson researchers are being aided in their efforts to explore some of the most important health care questions ranging from predicting the progression of dementia syndromes, examining the genetic progression of anaplastic thyroid cancer, and differentiating bipolar disorder from major depressive disorder in young adults.
Funded Project Grants
| Montero Odasso, Manuel (Funded through Lawson) |
Gait as a clinical marker to predict progression to dementia syndromes in MCI |
| Hoffman, Lisa Marie (Funded through Lawson) | Rescue of microvasculature enhances repair in muscle degenerative disorders |
| Anderson, Kelly | Understanding the Role of the Family Physician in Early Psychosis Intervention: A Mixed Methods Study |
| Gunaratnam, Lakshman | The Role of Kidney Injury Molecule-1 in Renal Transplantation |
| Heinrichs, David | Iron acquisition and storage mechanisms in Staphylococcus aureus pathogenesis |
| Hess, David A | Formulation of a vascular regenerative niche within implantable human decellularized adipose tissue bioscaffolds |
| Macdermid, Joy | Narcotic versus non-narcotic medication for pain management after wrist/hand fractures: a randomized noninferiority clinical trial |
| Nichols, Anthony | The Evolution of the Most Lethal Human Malignancy: The Genetic Progression of Anaplastic Thyroid Cancer |
| Palaniyappan, Lena | Myelin Mapping and Negative Symptoms of Schizophrenia |
| Ronald, John | Blood-based detection and molecular imaging visualization of cancer using reporter gene vectors called tumor-activatable minicircles |
| Seguin, Cheryle | Ectopic calcification of spinal tissues: etiology and potential therapeutic targets |
| Wang, Rennian | Studies of the functional role of pancreatic stellate cells (PaSCs) during islet differentiation, regeneration and diabetes |
Funded Bridge Grants
| Osuch, Elizabeth (Funded through Lawson) |
Differentiating Bipolar Disorder from Major Depressive Disorder in depressed, medication-free young adults using multivariate brain imaging and machine learning technologies |
| Gilliland, Jason | Development and Evaluation of a Smartphone Based Program for Improving Food Literacy and Healthy Eating Among Youth |
| Dick, Frederick | Roles of retrotransposon silencing in genome instability and cancer therapy |
| Drangova, Maria | Characterizing cerebral thrombus composition with Phase-based MRI |
Class of medication used for overactive bladder linked to new onset of dementia
A study from Western University, Lawson Health Research Institute and ICES provides further evidence of a link between a common class of medications called anticholinergics and the onset of dementia.
Anticholinergic medications are those that act on the body’s cholinergic receptors, and are used to treat a range of conditions from allergies and nausea to overactive bladder and psychiatric disorders.
Using ICES data for more than 60,000 Ontarians, Dr. Blayne Welk looked at a specific group of patients with a condition known as overactive bladder. This condition, which affects one in ten Canadians, can be treated with two different classes of medication – anticholinergic medication, and another medication class known as beta-3 agonists. Both medications are effective for treating overactive bladder.
The results of the study showed an increase in the number of new cases of dementia for patients being treated with an anticholinergic medication compared to those being treated with beta-3 agonists. While the overall risk for dementia was low, the rate was 20 per cent higher for patients treated with an anticholinergic medication. During the study, 2.3 per cent of people developed dementia if they used an anticholinergic, as compared to 1.6 per cent of people who used a beta-3 agonist medication.
“The unique thing about this study is that with overactive bladder there is a new medication that isn’t an anticholinergic, so it allowed us to do a very good comparison between two groups of patients that all have the same condition at the start of the study,” said Dr. Welk, an Associate Professor at the Schulich School of Medicine & Dentistry at Western and Scientist at Lawson Health Research Institute. “We were able to confirm with more certainty that there is an increased risk of dementia with the use of anticholinergic medication.”
Dr. Welk hopes this study will help to further emphasize the cognitive risks associated with this class of drugs, and to encourage physicians to consider alternative medications or appropriate deprescribing where possible.
“The hope is to draw attention from the medical community to consider the cognitive side-effects when prescribing anticholinergic medications,” Dr. Welk, who is also an Adjunct Scientist at ICES said. “With overactive bladder, we have an alternate medication choice now that works through a different pathway. If a patient has cognitive dysfunction, it may be appropriate to consider using a non-anticholinergic medication first for the treatment of overactive bladder symptoms.”
Clinical Research
Research at Lawson spans the continuum of life and mirrors the clinical areas of across St. Joseph’s Health Care London. Lawson is involved in all types and phases of clinical trials. Ethical clinical research and participant safety are our utmost priority.
Where does clinical research happen?
Depending on the research being done, it can take place in many different locations, including:
- Doctor’s offices
- Hospitals
- Medical centres
- Community nusing stations
- Academic centres, such as universities and medical schools
- Clinics
- At your home
Frequently Asked Questions
- What is a clinical trial?
- Participating in clinical trials
- Regulations and guidelines
- Considerations for participants and questions to ask
- Clinical Trials Ontario
- It Starts With Me
- Where can I find open clinical trials?
Contact
If you have questions, please call 519-667-6649 or email @email.