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Research from the HULC Clinical Research Laboratory has been featured frequently in the news media.
2023 Ontario Women’s Health Scholars Award winners — Hoda Seens
Anxiety levels increasing during COVID-19 pandemic — Hoda Seens
Writing Lay Summaries — Dr. Joy MacDermid
Study looks to extinguish persistent firefighter pain — Dr. Joy MacDermid
Dr. MacDermid was named a Fellow of the Royal Society of Canada in 2019 — Dr. Joy MacDermid
Top ranking Ph.D. award from the Canadian Institutes of Health Research (CIHR) — Pavlos Bobos
Meet the Team
The HULC Clinical Research Laboratory includes a multidisciplinary team of surgeons, therapists, engineers, scientists, technicians and graduate students working alongside research participants to improve patient care.
Meet the Research Team
Researchers
Joy C. MacDermid
Location: St. Joseph’s Health Care London
Role: Co-director
Phone: 519-661-2111 EXT: 64636
Degree and Qualifications: BSc, BScPT, MSc, PhD
Email: @email
Academic publication:
Google Scholar Homepage: https://scholar.google.ca/citations?user=O8LegU4AAAAJ&hl=en
PubMed: http://www.ncbi.nlm.nih.gov/pubmed?cmd=PureSearch&term=macdermid+j%5bAu…
My research aims to reduce the burden of musculoskeletal (MSK) pain, injury and chronic disease in studies that:
- Develop and test useful and valid measures of MSK symptoms and work role function.
- Identify modifiable biologic, psychosocial and environmental risk factors; and test how these are mediated by sex/gender.
- Test workplace, surgical and rehabilitation interventions that optimize ability and function.
- Assess musculoskeletal health at a population level
- Conduct knowledge translation research that guides efficient and effective implementation.
I conduct my work in collaboration with HULC researchers and clinicians, trainees and committed research teams that conduct national clinical trials, and research institutes comprised of high-quality researchers including IC/ES, The Bone and Joint Institute, and CIPSRT.
Staff
Katrina Munro
Name: Katrina Munro
Location: St. Joseph’s Health Care London
Role: Clinical Research Coordinator
Phone: 519-646-6100 EXT: 64544
Email: @email
Ze Lu (Steve)
Name: Ze Lu (Steve)
Location: St. Joseph’s Health Care London
Role: Clinical research assistant
Phone: 519-646-6100 EXT: 64544
Email: @email
Bansari Patel
Name: Bansari Patel
Location: St. Joseph’s Health Care London
Role: Clinical research assistant
Phone: 519-646-6100 EXT: 64544
Email: @email
Sahar Johari
Name: Sahar Johari
Location: St. Joseph’s Health Care London
Role: Clinical research assistant
Phone: 519-646-6100 EXT: 64544
Email: @email
Students
The HULC Clinical Research Laboratory provides education and training to the next generation of clinical researchers. Under the direction of Dr. Joy MacDermid, the lab produces high-quality research on measuring, predicting and reducing upper extremity disability with a focus on surgery and rehabilitation. Students and trainees play an important role on our team. They include post-doctoral fellows, Ph.D. and Master’s candidates, co-op students, clinical fellows, residents, medical students, and physiotherapy students.
Trainees
The HULC Clinical Research Laboratory provides education and training to the next generation of clinical researchers. Under the direction of Dr. Joy MacDermid, the lab produces high-quality research on measuring, predicting and reducing upper extremity disability with a focus on surgery and rehabilitation. Students and trainees play an important role on our team. They include post-doctoral fellows, Ph.D. and Master’s candidates, co-op students, clinical fellows, residents, medical students, and physiotherapy students.
Current Trainees
Daniel Briatico
Past Trainees
Aksha Mehta
Bansari Patel
Hajra Batool
Mahdiyeh Shafiezadeh Bafghi
Safa Jamaluddin
Opportunities
All of the HULC labs provide excellent training opportunities. See each of our lab websites for details.
There are about 20-25 trainees in the Clinical Research Lab. The lab has opportunities available for post-doctoral fellows, PhD and master’s candidates, co-op students, clinical fellows, residents, medical students and physiotherapy students.
Students can pursue a master’s or Ph.D. with Dr. MacDermid by enrolling in the Faculty of Health Sciences. Dr. MacDermid supervises students in multiple fields including Physical Therapy, Measurement and Methods, and Health Promotion. For more details on these programs and the admission requirements and process consult with the website and program staff. Funding is available for students who meet program requirements.
https://www.uwo.ca/fhs/programs/hrs/programs.html
Post-docs are individually arranged and dependent on funding.
Medical trainees can take research training by enrolling in the Masters in Surgery:
https://www.schulich.uwo.ca/surgery/education/msc_in_surgery/index.html
Training and Permissions
As a hospital-based clinical research lab, HULC adheres to the policies of St. Joseph’s Health Care London and Lawson Health Research Institute. Students and trainees are required to complete the appropriate training and permissions through Medical Affairs at St. Joseph’s.
Learn more about orientation information at St. Joseph’s, including required learning.
If you have any questions related to training or permissions in your role at HULC, please speak to your supervisor.
Partners
Metabolic syndrome commonly associated with early rheumatoid arthritis
A Canada-wide multicentre study of patients with early rheumatoid arthritis (ERA) has found an association between metabolic syndrome and rheumatoid arthritis, and that the prevalence is most common among men and postmenopausal women.
September is National Arthritis Awareness Month in Canada. With rheumatoid arthritis, the patient’s joints and organs are “attacked” by their own immune system. This is the most common type of autoimmune arthritis. Persons with the disease typically experience swollen joints, pain and stiffness, and chronic fatigue. In later stages of the disease, incessant inflammation breaks down the joint, causing permanent damage, and can impair nerves and blood vessels. It is important for patients to begin treatment as early as possible.
The Canadian Early Arthritis Cohort (CATCH) study collects data on over 3,000 patients across Canada with ERA. Patients in this cohort are defined as a person who is within one year of symptom onset.
Dr. Lillian Barra, Associate Scientist at Lawson Health Research Institute (Lawson), and Rheumatologist at St. Joseph’s Hospital London, was interested in learning about the association between ERA and other diseases and conditions that are commonly found among patients with ERA. Metabolic syndrome refers to a cluster of conditions that often occur together and increase the risk of heart disease, stroke, and type 2 diabetes. These include heart disease, high blood pressure, abnormal cholesterol, obesity and high blood sugar.
“It is interesting that we found these conditions of metabolic syndrome so early in the course of this disease. While previous researchers have demonstrated an association, it remains a question whether metabolic syndrome contributes to rheumatoid arthritis, or vice versa.” explains Dr. Barra.
“This information can help inform clinicians managing patients with rheumatoid arthritis. In the future, we hope to develop more precise guidelines around when these comorbidities should be screened for and co-managed over the course of treatment.”
Currently, if a newly diagnosed rheumatoid arthritis patient presents with severe symptoms, they are given therapies that work quickly to reduce the inflammation in addition to long-term disease modifying drugs that are the standard of care. These therapies include corticosteroids, such as prednisone, and non-steroidal anti-inflammatories (NSAIDs), such as Advil or Motrin. For the clinician, it is important to consider if the patient has any conditions of metabolic syndrome, as these fast-acting therapies are known to increase the risk of heart disease and stroke. The treatment approach may be altered if these conditions are present.
Dr. Barra plans to re-examine the CATCH data at a later time, to determine if metabolic syndrome and rheumatoid arthritis worsens or improves over time. In future research, she also hopes to discover some of the causes and mechanisms at play, to better understand why many patients with rheumatoid arthritis also have metabolic syndrome.