Search
Search
First-in-North-America resource touts health benefit of fermented foods
New network helps consumers, researchers and food industry find and share trusted information about ‘ferment-ceuticals’
London (Ont.) – A one-stop network, the first of its kind in North America, has begun sharing easily digested research, recipes and other resources about the health benefits of fermented foods.
The new Canadian Fermented Foods Initiative (CFFI) launches officially on Nov. 17 with a gathering of research and industry experts from across the country and Europe.
The collaboration helps consumers, researchers, health professionals and food industry share trusted, science-based expertise and information about fermented foods.
Funded by the Weston Family Foundation, the initiative is led by Jeremy Burton, PhD, who heads of one of Canada’s largest microbiome research programs and is Interim Vice President Research at St. Joseph’s Health Care London and Lawson Research Institute. His research leadership is joined by Raylene Reimer, PhD, professor of nutrition at the University of Calgary; and University of Alberta professor Ben Willing, PhD, former Canada Research Chair in Microbiology of Nutrigenomics.
Fermented foods such as sourdough bread, sauerkraut, kimchi and kombucha offer more than just good taste and an economical way to preserve food, Burton says. Large, population-based studies show people who eat fermented foods are generally healthier, with fewer digestive issues and lower risk of chronic diseases.
“How exactly does that work – and why? Well, that’s the big question we’re trying to solve,” Burton says. “One day, I believe, ‘ferment-ceuticals’ will be engrained in our diets and our health vocabulary.”
St. Joseph's is a leader in the field. A paper authored by the team and published this week in Advances in Nutrition represents the most comprehensive synthesis to date of research on fermented foods and human health.
Connor Flynn, a London, Ont., chef, master food preserver and high school teacher whose video recipes are included in the CFFI website, adds, “Fermenting foods is an old practice that’s never fallen out of flavour, but has sometimes fallen out of favour to North Americans. Now it has become popular again.”
To learn more about the CFFI, including fermented food recipes and the chef behind them, head to fermentedfoods.ca.
- 30 -
To arrange interviews with CFFI project lead Jeremy Burton and chef Connor Flynn, who are available Friday Nov. 14 from 7 am – 8 am ET and Nov. 14 from 1 – 4 pm ET, contact:
Deb (Flaherty) Van Brenk, Communication Consultant
St. Joseph’s Health Care London
@email
About St. Joseph’s Health Care London
Renowned for compassionate care, St. Joseph’s Health Care London is a leading academic health care centre in Canada dedicated to helping people live to their fullest by minimizing the effects of injury, disease and disability through excellence in care, teaching and research. Through Lawson Research Institute, our innovation arm, and with collaborative engagement with other health and academic partners, St. Joseph’s has become an international leader in the areas of: chronic disease management; medical imaging; specialized mental health care; rehabilitation and specialized geriatrics; and surgery. St. Joseph’s operates through a wide range of hospital, clinic and long-term and community-based settings, including: St. Joseph’s Hospital; Parkwood Institute; Mount Hope Centre for Long Term Care; and the Southwest Centre for Forensic Mental Health Care.
For Researchers
HULC publishes high-impact clinical research and trains the next generation of clinicians and researchers, to improve management of painful, disabling conditions affecting the arm/hand. Our research leads to new devices, treatments and processes for managing injuries (like fractures and work injuries) or diseases (like arthritis and osteoporosis) that impair the function of the person, their arm and/or hand See links on this page for outputs and summaries of this work, and work in progress. We conduct:
- Measurement of patient outcomes and perspectives
- Clinical trials of new surgery and rehabilitation interventions
- Studies identifying the predictors of health and work outcomes
Learn more about research studies from the HULC clinical research lab:
- Outcome measures
- Tools and Products of Research
- Patient program
- COVID-19 project
- Training Resources
- Open Access Publications
- Lay Summaries
- Past Study Reports
- Media
- Presentations
- Item Perspective Classification framework (IPC) Information Site
Funding for unique strategy to prevent homelessness after hospital discharge
In Canada, about 235,000 people experience homelessness each year. The number of homeless people, and the length of time they spend homeless, continues to rise. Homelessness is not a choice and anyone can become homeless.
Although the root cause is poverty, some underlying issues are poor physical or mental health; violence or abuse in the home; lack of employment or income; and, a shortage of affordable housing.
A group of researchers at Lawson Health Research Institute (Lawson), working at both London Health Sciences (LHSC) and St. Joseph’s Health Care London (St. Joseph’s), are committed to tackling the issue of homelessness from within hospital walls, where some patients face the risk of being discharged into homelessness.
“Many of our patients with lived experience of homelessness were saying that their journey started with a hospital discharge,” says Lawson clinician researcher Dr. Cheryl Forchuk. “Often, they were experiencing major transitions in their lives and then experienced a hospital stay. Normally a relatively short visit, they aren’t able to gather the information and make a plan to be able to leave the hospital with somewhere to stay.”
On September 10, Adam Vaughan, Canadian MP and Parliamentary Secretary (Housing and Urban Affairs), on behalf of the Honourable Jean-Yves Duclos, Minister of Families, Children and Social Development, announced that Lawson will receive $223,572 from the Homelessness Partnering Strategy’s (HPS) Innovative Solutions to Homelessness funding stream to support the project “No Fixed Address Version 2 Expansion” research project.
“This is a brilliant approach. It supports an augmented duty of care where hospitals have the means to transfer people into stable settings where they can continue to heal and move towards self-sufficiency,” says Parliamentary Secretary Vaughan.
Taking place at London Health Sciences Centre, this research will further refine the No Fixed Address strategy for reaching and supporting patients during the crucial transitional period when they are being discharged from the hospital and re-integrated into the community.
“Lawson’s expanded No Fixed Address research project is the first evaluation anywhere of a strategy to reduce the number of patients being discharged into homelessness. There is almost no literature on any aspect of this troublesome issue,” explains Dr. Forchuk who is the study’s Principal Investigator. Dr. Forchuk is also the Beryl and Richard Ivey Research Chair in Aging, Mental Health, Rehabilitation and Recovery and Assistant Director at Lawson.
This project is an extension of three previous studies conducted by Dr. Forchuk’s research team, which developed and tested this novel approach. They demonstrated the efficacy, feasibility and cost-effectiveness of using the No Fixed Address strategy in acute and tertiary psychiatric care in the London region, at both LHSC and St. Joseph’s. In the first phase, they found that the interventions used prevented homelessness in 95 per cent of cases.
The researchers are now taking a solution proven to have worked in the mental health units and applying it in selected medical departments at LHSC. Through the study, the services will be available to all patients in those units who are at risk of homelessness. There have already been 17 patients who have accessed this support since the project got underway this summer.
Three community partners from London are supporting implementation of the strategy - Canadian Mental Health Association Middlesex, Ontario Works in the City of London and the Salvation Army’s Housing Stability Bank. They will provide assistance in areas like securing appropriate private-sector housing, provision of income and employment supports, and financial assistance.
“In many ways London, Ontario is the high water mark of solving and tackling homelessness. This community has a lot of be proud of given the way that the municipality is stepping up to the plate and how many different organizations are working together towards a common goal,” says Parliamentary Secretary Vaughan.
This kind of collaboration showcases the important partnership between the Canadian Government, research-intensive hospitals and community organizations to translate innovative solutions from the research stage to the front line of care.
“The hope is that the findings will be even more robust, leading to the development of a best-practice model of hospital discharge that can be adopted throughout Canada. This will reinforce the need for a systemic change in the way hospital discharges occur and ensuring the person is transitioning to a secure housing arrangement,” says Dr. Forchuk.
Learn more about the Government of Canada’s Homelessness Partnering Strategy.
News Coverage
- CBC London - Helping medical patients in London avoid homelessness when they leave hospital
- CTV London - Expanded research hopes to break the cycle of homelessness that psychiatric patients sometimes face when discharged
- Global News, AM 980 - Program that finds housing for homeless patients in hospital gets $223K in federal funding
- London Free Press - 'Brilliant approach' to homelessness gets federal grant
Health researchers in London bring in over $11 million of national funding
The Canadian Institutes of Health Research (CIHR) announced more than $11.3 million in funding through their project grants program for 17 health research projects across Lawson Health Research Institute and Western University.
“The funded projects represent a wide range of research and expertise from London’s health research community, with real impacts for health and health care,” says Dr. David Hill, Lawson Scientific Director. “Congratulations to those successful applicants who have secured this funding on a very tough competition.”
Projects include a national study on transgender health; a community-based family treatment program for children with epilepsy; imaging of blood clots in the brain; equity in mental health care for children and youth; and, a smartphone intervention focused on diet and food literacy.
See the full list of successful applicants.
Cooling the Brain after Resuscitated Cardiac Arrest to Prevent Brain Injury
There are 40,000 cardiac arrests each year in Canada. A high number of patients won’t survive the event and nearly half of the survivors suffer from brain damage that can have a huge impact on their ability to live independently. The current guidelines recommend cooling of the whole body to protect the brain against the damaging effects of cardiac arrest. However, in the clinic there are several hurdles for this treatment that can create complications. Enhanced brain protection may be achieved by selectively cooling the brain but a simple, effective and non-invasive method to do so is needed.
Dr. Ting-Yim Lee and his research team are studying a simple means to cool down the brain by blowing compressed air into the nostrils which would essentially chill the warm blood coming through the nasal cavity on its way to the brain. Using an animal model, their aim is to show that the method can be used safely and is able to protect the brain after cardiac arrest.
Image
The DECIPHER Study
Shoulder fractures are becoming increasingly common for older adults and cause considerable limitations and impacts for their daily life. While different approaches are taken to treat shoulder fractures, there is a lack of knowledge and evidence to show which of those methods are the most effective and for which patients.
Dr. Emil Schemitsch and his research team are proposing the first nation-wide, multi-centre observational study with over 600 patients with the ultimate goal of determining what specific factors influence important outcomes for patients. The DECIPHER study will seek to answer important questions about which treatment and rehabilitation strategies are best for different patients, strengthening the clinical strategy for managing these difficult and prevalent injuries. It will also provide an economic analysis to understand the impact for healthcare system costs.
Congratulations to all of the successful applicants:
- Greta Bauer and Ayden Scheim - Trans PULSE Canada: A National Study of Transgender Health
- Maria Drangova - Characterizing cerebral thrombus composition with Phase‐based MRI
- David Edgell, Bogumil Karas, and Gregory Gloor - ConCRISPR: Conjugative delivery of a hybrid CRISPR/Tev nuclease system for specific microbiota modulation in the mammalian gut
- Jason Gilliland - Evaluation of a Smartphone Based Intervention for Improving Food Literacy, Food Purchasing, and Diet Quality Among Youth in Urban, Suburban, and Rural Environments
- Douglas Hamilton - Novel Biomaterials‐Based Strategies to Stimulate Periodontal Tissue Regeneration
- David Haniford - Regulation of Salmonella pathogenesis by transposon‐encoded small regulatory RNAs
- Steven Laviolette - Effects of Neurodevelopmental Exposure to Cannabinoids on Prefrontal Cortical Function: Implications for Neuropsychiatric Disorders
- Ting-Yim Lee - Selective Brain Hypothermia via Intranasal Cooling to Limit Brain Injury Post Cardiac Arrest (Funded through Lawson Health Research Institute)
- Stephen Lomber - Cortical Plasticity Following Deafness
- Vania Prado - Cholinergic influence in aging and brain pathology
- Graham Reid and William Gardner - Equity in Mental Health Care for Children and Youth
- Jason Roberts - The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest: The EPS ARREST Study
- Emil Schemitsch - The DECIPHER Study: DEterminants of Function and Clinically Important outcomes in Proximal Humerus Fractures in the Elder Population: A National CohoRt (Funded through Lawson Health Research Institute)
- Walter Siqueira and Elizabeth Gillies - Novel Drug Delivery System for the Combat of Dental Caries by using Salivary Peptides
- Kathy Speechley and Karen Bax - A Community-Based Family Treatment Program for Children with Epilepsy: A Randomized Controlled Trial
- Andrew Watson - Understanding and Treating Obesity Related loss of Embryo Developmental Competence
- Donald Welsh - Kir Channel Regulation by Membrane Lipids: An Enabler of Hemodynamic Sensing in the Cerebral Circulation
Heather MacKenzie
Heather MacKenzie, MD; MSc
Assistant Professor, Schulich School of Medicine and Dentistry
Acquired and Traumatic Brain Injury
Dr. Heather MacKenzie is a physiatrist at Parkwood Institute and an Assistant Professor in the Department of Physical Medicine and Rehabilitation in the Schulich School of Medicine and Dentistry at Western University. She completed her residency training in Physical Medicine and Rehabilitation at Western University and subsequently earned a Master’s of Science degree in Epidemiology at the Harvard T. H. Chan School of Public Health.
Her research program focuses on predicting outcomes after concussion/mild traumatic brain injury (mTBI). Although concussions/mTBIs are common and the majority of symptoms resolve within three months, a significant proportion of individuals remain symptomatic beyond one year. These persistent symptoms result in mobility challenges and reduced participation in instrumental activities of daily living as well as vocational and leisure activities. Dr. MacKenzie’s current research focuses on identifying patients that are at high-risk for developing persistent symptoms from concussion/mTBI so that interventions can be prioritized and rehabilitation services can be quickly mobilized. Early intervention for those expected to have a prolonged recovery has the potential to alter their trajectory and optimize their potential for a positive outcome and may also reduce the occurrence of persistent symptoms and decrease secondary disability related to their injury.
History
Each hospital’s research mission has a rich history. At both hospital organizations, leaders recognized opportunities to leverage in-house experts to conduct research and improve care. However, they also recognized the challenge in supporting these activities without dedicated space and resources.
Through great foresight, our hospitals founded the official research institutes that serve as Lawson's foundation:
- 1983: Supported by Sister Mary Doyle, former Executive Director of St. Joseph's, the Sisters of St. Joseph's establish the hospital's official research institute. LHSC and Upjohn jointly open the Victoria Upjohn Clinical Research Unit at South Street Hospital (formerly Victoria Hospital), focusing on Phase I-III clinical trials.
- 1987: The St. Joseph's research institute is named the Lawson Research Institute (LRI) in honour of London businessman and philanthropist Colonel Tom Lawson and his wife, Miggsie Lawson - close friends of Sister Mary Doyle and major supporters of the research mission.
- 1990: Victoria Hospital takes over the operation of the clinical research unit at South Street, renaming it the Victoria Clinical Trials Centre.
- 1997: The Victoria Clinical Trials Centre is renamed London Health Sciences Centre Research Inc. and becomes a fully incorporated research institute overseeing all hospital-based research within London Health Sciences Centre sites: Victoria Hospital, University Hospital and South Street Hospital.
- 2000: LRI and LHSCRI merge to form a joint venture: Lawson Health Research Institute.
- 2014: Lawson Research Institute (re-)launches as the hospital-based research arm of St. Joseph's with the goal of transforming imagination to innovation to impact; and as LHSCRI is also embedded into LHSC.
Today, partnerships remain strong, allowing researchers to move seamlessly between hospital locations and Western University.
Milestones
Since forming in 2000, Lawson has pioneered breakthroughs across various disciplines of health research and reached several institutional milestones.
- 2019: Lawson led research team is the first in the world to develop a new imaging tool, showed that MRI can be used to measure how the heart uses oxygen.
- 2019: New studies from Lawson and Western University found for the first time that HIV can be transmitted through the sharing of equipment used to prepare drugs before injection and that a simple intervention can destroy the HIV virus, preventing that transmission.
- 2019: In the first genomic analysis of head and neck cancer by smoking status, researchers at Lawson, in collaboration with researchers at the Ontario Institute for Cancer Research and UCLA Cancer Centre, carried out a comprehensive genetic analysis of HPV-negative tumours to better understand the link between smoking and cancer recovery.
- 2019: Lawson scientists develop molecular diagnostic tool to analyze epigenetic patterns, facilitating diagnosis of rare, unknown hereditary disorders. London Health Sciences Centre is the first site in the world to offer this type of testing.
- 2018: Research shows high-dose radiation can improve survival in patients with cancer that has spread to give or less sites. The SABR-COMET study was the first randomized phase II clinical trial of its kind.
- 2018: An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.
- 2018: In collaborative study between Lawson and Stanford University, scientists develop and test a new synthetic surfactant that could lead to improved treatments for lung disease and injury.
- 2018: Scientists use brain MRI to develop first ever method examining young people before they become ill to reliably identify who will develop acute psychosis and who will not.
- 2018: Research team develops clinically-validated, open-source 3D printed stethoscope for areas with limited access to medical supplies.
- 2018: Lawson opens Clinical Research and Chronic Disease Centre (CRCDC) at St. Joseph’s Hospital to tackle chronic disease and improve patient care.
- 2018: Lawson researchers receive $4.4 million to study personalized medicine at LHSC, examining the value of prescribing treatments based on a patient’s genetics.
- 2017: In one of the largest microbiota studies conducted in humans, researchers at Western University, Lawson Health Research Institute and Tianyi Health Science Institute in Zhenjiang, Jiangsu, China have shown a potential link between healthy aging and a healthy gut.
- 2017: Lawson researchers develop transition program to help young adults with type 1 diabetes move from paediatric to adult care.
- 2017: Innovative study brings next-generation genome sequencing to London cancer patients, contributing to province-wide database of genomic and clinical data.
- 2017: Technology developed at Western University and Lawson Health Research Institute can provide a new window into whether or not patients are responding to treatment for advanced ovarian cancer.
- 2017: Dr. Alan Getgood and his team at Western University and Lawson Health Research Institute are the first in Canada to participate in an investigative trial to determine the safety and efficacy of using a patient’s own cartilage cells to repair knee cartilage injuries.
- 2016: Lawson Researchers at Parkwood Institute are the first in Canada to develop clinical practice guidelines for managing neuropathic pain with patients who have experienced a spinal cord injury.
- 2016: Researchers at Lawson are the first in Canada to use a Prostate Specific Membrane Antigen (PSMA) probe in Positron Emissions Tomography (PET) scans to provide improved and highly specific images used for better diagnosis and management of prostate cancer.
- 2015: Lawson scientists, in collaboration with Ceresensa Inc., produce novel PET-transparent MRI head coil, a world first in imaging technology
- 2015: Lawson announces partnership with STEMCELL Technologies for commercialization of tools for Parkinson’s disease research
- 2015: Novare Pharmaceuticals and Lawson announce issuance of a U.S. patent for the composition-of-matter and use of RHAMM-binding peptides with a wide range of potential therapeutic uses. The patent also has claims for the diagnosis and prognosis of cancer, and for prescribing a course of treatment for the diagnosed cancer.
- 2014: Lawson announces licensing agreement with Yabao Pharmaceutical Group in China to develop and test a new life-saving drug to treat sepsis
- 2014: Lawson researchers are part of a Canadian team who have developed a way to produce a key medical isotope, technetium-99m (Tc-99m), using hospital based cyclotrons
- 2013: The Institute for Clinical Evaluative Sciences (ICES) Western opens at Lawson
- 2012: Lawson installs Canada's first PET/MRI at St. Joseph's Hospital
- 2011: Lindros Legacy Research Building officially opens at University Hospital
- 2010: Lawson opens the Cyclotron and PET Radiochemistry facility at St. Joseph's Hospital
- 2009: Lawson receives a record $7 million donation to support the Canadian Research & Development Centre for Probiotics
- 2008: Lawson establishes an experimental anti-thrombolitic clinic to calculate personalized dosage of drugs based on a patient's genetics
- 2007: The first totally endoscopic closed-chest robotic coronary artery bypass surgery on a patient's beating heart is performed at University Hospital
- 2006: Lawson opens the Aging, Rehabilitation & Geriatric Care Research Centre, the first centre of its kind in Canada, at Parkwood Institute
- 2005: Lawson creates the first Ontario Cardiac Rehabilitation Registry
- 2004: Lawson scientists release a three-year study on the effects of the Walkerton water disaster
- 2003: Lawson opens the Victoria Research Laboratories at Victoria Hospital, the first collaboration of its kind in Canada bringing together research from cancer, children's health and vascular biology
- 2002: Lawson installs the first Positron Emission Tomography and Computer Tomography (PET/CT) scanner in Canada at St. Joseph's Hospital
- 2001: St. Joseph's is one of five sites in the world piloting the Diabetes Electronic Management Systems
Home Monitoring in Health Care Conference
Research has shown that technology can link clinicians to a changing clinical situation in real-time, enabling provision of appropriate and timely medical care. But how can we implement this here in London?
Join us on November 24, 2018 to learn from local innovators on their current projects and help us collaborate on future goals.
Saturday, November 24, 2018
9:00 a.m. - 1:45 p.m.
(Registration beginning at 8:30 a.m.)
Sumner Auditorium, Victoria Hospital, Rm. B2-119
800 Commissioners Rd. E, London, Ontario
Moderator:
- Dr. Homer Yang, Anesthesia & Perioperative Medicine, LHSC
Speakers:
- Dr. Nassar Khalil, Connecting Care to Home
- Dr. James Lewis, Connecting Care to Home
- Dr. Julieann Vankoughnett, Surgery, LHSC
- Dr. Anthony Tang, Cardiology, LHSC
- Dr. Tim Doherty, Physical Medicine & Rehabilitation, LHSC
- Dr. Mandar Jog, Neurologist, LHSC
- Dr. John Fuller, Perioperative Care, LHSC
- Dr. Arsh Jain, Renal Services, LHSC
- Danish Mahmood, 15-year-old youth innovator, speaker, and high school student
For directions and parking information for Victoria Hospital, please see the LHSC website.
Improving mental health treatments for stroke patients is the focus of a new study
LONDON, ON- Strokes affect approximately 400,000 Canadians each year and can be debilitating. They can negatively affect a person’s cognition and mobility, and severely impact mental health and wellbeing.
A team at Lawson Health Research Institute are looking to improve mental health treatments and resources for patients who have experienced a stroke. The team will recruit 100 stroke patients to assess whether the completion of a guided therapy program can improve mental health and quality of life.
“More than sixty per cent of patients experience depression after stroke,” says Dr. Robert Teasell, Lawson Scientist and Physiatrist at St. Joseph’s Health Care London’s Parkwood Institute. “Having a stroke itself makes people more vulnerable and makes people feel their lives have changed negatively.”
During stroke rehabilitation, patients are typically offered mental health treatments, but the research team say it is post rehabilitation that stroke patients tend to experience worsening depression.
“Publicly funded allied health care services are available at inpatient and outpatient care; however, psychology is often limited across the rehabilitation continuum from acute to community care,” says Dr. Swati Mehta, Lawson Scientist. “We are looking at how we can provide a program that is cost effective to help those who have these barriers to access mental health services.”
“Patients have described to me that they feel like they have been dropped off a cliff because of the lack of resources once their programs have ended,” adds Dr. Teasell.
The study will examine the use of cognitive behavioral therapy (CBT), which is an evidence based psychological intervention that aims to provide people with increased coping ability and self-efficacy. Participants will complete a 10-week guided program with specific targeted lessons, tailored to the needs of those post stroke, delivered virtually through a trained clinician. They will then complete a questionnaire to see if there have been any improvements to self-efficacy and emotional wellbeing.
“We have found this form of therapy (CBT) has been very effective and feasible for spinal cord injury patients with mild traumatic brain injury and we want to see how a modified version could potentially help those with stroke and depression,” says Randy Upper, Clinical Research Associate at Lawson.
If CBT is proven effective through this study, Dr. Mehta hopes it will encourage similar programming that would be available to stroke patients after rehab.
“We are hoping we can connect with community organizations and work with them to implement this program in a service delivery model that would be easily accessible for stroke patients living in the community.”
Recruitment for this study is currently underway, those interested in taking part can email Dr. Swati Mehta at: @email
Senior Media Relations Consultant
Communications & Public Engagement
T: 519-685-8500 ext. 73502
Celine.zadorsky@lhsc.on.ca