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This handout explains Tapentadol, which is an Extended Release medication used to relieve moderate to severe pain in adults. Tapentadol is an atypical opioid medication because it has a unique mechanism of action: Tapentadol binds with certain opioid receptors to block pain signals from reaching the brain. This action is similar to that of opioid medications such as morphine. Tapentadol also works by increasing the brain levels of a chemical messenger called norepinephrine. This feature is similar to that of some antidepressant medications used to treat pain.

This handout explains Tapentadol, which is an Immediate Release medication used to relieve moderate to severe pain in adults. Tapentadol is an atypical opioid medication because it has a unique mechanism of action: Tapentadol binds with certain opioid receptors to block pain signals from reaching the brain. This action is similar to that of opioid medications such as morphine. Tapentadol also works by increasing the brain levels of a chemical messenger called norepinephrine. This feature is similar to that of some antidepressant medications used to treat pain.

Sacroiliac Joint joint injection involves administration of a local anesthetic (when done as a diagnostic procedure) or a mixture of local anesthetic and an anti-inflammatory medication known as a steroid (when done for treatment purposes). The medication is injected into the capsule of the SI joint.